finishes setup

2026-02-10 17:43:26 +01:00
parent 4f1a5c311f
commit 3003310be0
39 changed files with 2251611 additions and 1188 deletions
--- a/neo4j_csv/analysis_drug_repurposing.csv
+++ b/neo4j_csv/analysis_drug_repurposing.csv
--- a/neo4j_csv/analysis_super_drugs.csv
+++ b/neo4j_csv/analysis_super_drugs.csv
@@ -2,22 +2,22 @@ name,num_diseases_treated,num_side_effects,super_score
 Dacarbazine,7,0,7.0
 Sulfasalazine,4,0,4.0
 Cholecalciferol,3,0,3.0
-Cytarabine,2,0,2.0
 Atorvastatin,2,0,2.0
+Cytarabine,2,0,2.0
 Balsalazide,2,0,2.0
 Carboplatin,9,7,1.125
+Eribulin,1,0,1.0
+Guanethidine,1,0,1.0
 Doxycycline,1,0,1.0
 Isoetarine,1,0,1.0
-Moexipril,1,0,1.0
 Olsalazine,1,0,1.0
-Rifampicin,1,0,1.0
-Vitamin C,1,0,1.0
-Eribulin,1,0,1.0
 Artemether,1,0,1.0
-Guanethidine,1,0,1.0
+Moexipril,1,0,1.0
 Lopinavir,1,0,1.0
-Guanadrel,1,0,1.0
+Rifampicin,1,0,1.0
 Minoxidil,1,0,1.0
+Guanadrel,1,0,1.0
+Vitamin C,1,0,1.0
 Physostigmine,1,6,0.14285714285714285
 Dactinomycin,10,75,0.13157894736842105
 Vinblastine,7,59,0.11666666666666667
@@ -39,17 +39,17 @@ Methoxsalen,3,53,0.05555555555555555
 Mercaptopurine,3,57,0.05172413793103448
 Penbutolol,2,39,0.05
 Vincristine,7,142,0.04895104895104895
-Chlorambucil,4,83,0.047619047619047616
 Tiludronate,1,20,0.047619047619047616
+Chlorambucil,4,83,0.047619047619047616
 Cisplatin,8,169,0.047058823529411764
 Methylprednisolone,10,216,0.04608294930875576
+Calcipotriol,1,21,0.045454545454545456
 Beclomethasone,2,43,0.045454545454545456
 Methamphetamine,1,21,0.045454545454545456
-Calcipotriol,1,21,0.045454545454545456
 Fluocinonide,2,44,0.044444444444444446
 Lomustine,2,44,0.044444444444444446
-Dexamethasone,11,249,0.044
 Betamethasone,11,249,0.044
+Dexamethasone,11,249,0.044
 Teniposide,3,70,0.04225352112676056
 Miglitol,1,23,0.041666666666666664
 Benzphetamine,1,23,0.041666666666666664
@@ -58,16 +58,16 @@ Loratadine,3,73,0.04054054054054054
 Mechlorethamine,2,49,0.04
 Auranofin,2,50,0.0392156862745098
 Altretamine,1,25,0.038461538461538464
-Topotecan,4,111,0.03571428571428571
 Dyphylline,1,27,0.03571428571428571
+Topotecan,4,111,0.03571428571428571
 Mecamylamine,1,27,0.03571428571428571
 Spironolactone,2,56,0.03508771929824561
+Proguanil,1,28,0.034482758620689655
+Triamterene,1,28,0.034482758620689655
+Probenecid,1,28,0.034482758620689655
 Hydrocortisone,8,231,0.034482758620689655
 Diphenhydramine,2,57,0.034482758620689655
 Dimenhydrinate,2,57,0.034482758620689655
-Triamterene,1,28,0.034482758620689655
-Probenecid,1,28,0.034482758620689655
-Proguanil,1,28,0.034482758620689655
 Melphalan,4,117,0.03389830508474576
 Irinotecan,6,177,0.033707865168539325
 Mitoxantrone,6,177,0.033707865168539325
@@ -88,43 +88,43 @@ Bendroflumethiazide,1,34,0.02857142857142857
 Carmustine,5,177,0.028089887640449437
 Mometasone,3,107,0.027777777777777776
 Epirubicin,14,511,0.02734375
-Valsartan,3,110,0.02702702702702703
 Methimazole,1,36,0.02702702702702703
+Valsartan,3,110,0.02702702702702703
 Acetazolamide,2,74,0.02666666666666667
 Tolazamide,1,38,0.02564102564102564
-Chlorpropamide,1,38,0.02564102564102564
 Metipranolol,1,38,0.02564102564102564
+Chlorpropamide,1,38,0.02564102564102564
 Linagliptin,1,39,0.025
-Disulfiram,1,39,0.025
 Propantheline,1,39,0.025
+Disulfiram,1,39,0.025
 Rosuvastatin,2,80,0.024691358024691357
 Hydroflumethiazide,1,40,0.024390243902439025
 Vinorelbine,4,164,0.024242424242424242
 Amobarbital,1,41,0.023809523809523808
 Acarbose,1,42,0.023255813953488372
 Acetylsalicylic acid,2,86,0.022988505747126436
-Reserpine,1,43,0.022727272727272728
 Phenylpropanolamine,1,43,0.022727272727272728
 Ethacrynic acid,1,43,0.022727272727272728
+Reserpine,1,43,0.022727272727272728
 Montelukast,3,132,0.022556390977443608
 Colchicine,2,88,0.02247191011235955
 Calcium Acetate,1,44,0.022222222222222223
 Ruxolitinib,1,44,0.022222222222222223
 Vemurafenib,2,90,0.02197802197802198
-Primidone,1,45,0.021739130434782608
 Tazarotene,1,45,0.021739130434782608
+Primidone,1,45,0.021739130434782608
 Thiotepa,4,184,0.021621621621621623
 Metformin,3,139,0.02142857142857143
-Carteolol,1,46,0.02127659574468085
 Nateglinide,1,46,0.02127659574468085
+Carteolol,1,46,0.02127659574468085
 Alendronate,2,94,0.021052631578947368
-Aminophylline,2,95,0.020833333333333332
 Fenoldopam,1,47,0.020833333333333332
-Ketotifen,1,48,0.02040816326530612
+Aminophylline,2,95,0.020833333333333332
 Diclofenamide,1,48,0.02040816326530612
+Ketotifen,1,48,0.02040816326530612
 Phentermine,1,48,0.02040816326530612
-Raloxifene,2,98,0.020202020202020204
 Idarubicin,2,98,0.020202020202020204
+Raloxifene,2,98,0.020202020202020204
 Captopril,3,148,0.020134228187919462
 Pitavastatin,1,49,0.02
 Erlotinib,3,152,0.0196078431372549
@@ -132,39 +132,39 @@ Nebivolol,1,50,0.0196078431372549
 Glyburide,2,102,0.019417475728155338
 Ramipril,4,206,0.01932367149758454
 Carbachol,1,51,0.019230769230769232
-Desonide,1,52,0.018867924528301886
 Valrubicin,1,52,0.018867924528301886
+Desonide,1,52,0.018867924528301886
 Zileuton,1,52,0.018867924528301886
 Calcitriol,2,106,0.018691588785046728
 Levobunolol,1,53,0.018518518518518517
 Timolol,4,218,0.0182648401826484
-Propylthiouracil,1,54,0.01818181818181818
 Vismodegib,1,54,0.01818181818181818
+Propylthiouracil,1,54,0.01818181818181818
 Indacaterol,1,54,0.01818181818181818
 Tiotropium,2,110,0.018018018018018018
 Orciprenaline,1,55,0.017857142857142856
 Pentoxifylline,2,111,0.017857142857142856
 Propranolol,2,112,0.017699115044247787
 Furosemide,3,171,0.01744186046511628
-Torasemide,1,58,0.01694915254237288
 Nedocromil,1,58,0.01694915254237288
-Pirbuterol,1,59,0.016666666666666666
+Torasemide,1,58,0.01694915254237288
 Methazolamide,1,59,0.016666666666666666
+Pirbuterol,1,59,0.016666666666666666
 Temozolomide,4,241,0.01652892561983471
 Lovastatin,2,121,0.01639344262295082
 Losartan,3,187,0.015957446808510637
-Trimethadione,1,62,0.015873015873015872
 Chlorothiazide,1,62,0.015873015873015872
+Trimethadione,1,62,0.015873015873015872
 Ezetimibe,2,127,0.015625
 Entecavir,1,63,0.015625
 Latanoprost,1,64,0.015384615384615385
 Chlorthalidone,1,65,0.015151515151515152
-Fluticasone furoate,1,65,0.015151515151515152
 Lisinopril,4,263,0.015151515151515152
+Fluticasone furoate,1,65,0.015151515151515152
 Sorafenib,3,198,0.01507537688442211
 Bumetanide,1,66,0.014925373134328358
-Estramustine,1,66,0.014925373134328358
 Repaglinide,1,66,0.014925373134328358
+Estramustine,1,66,0.014925373134328358
 Prazosin,1,66,0.014925373134328358
 Flunisolide,2,133,0.014925373134328358
 Eplerenone,2,134,0.014814814814814815
@@ -172,25 +172,25 @@ Vorinostat,1,67,0.014705882352941176
 Adefovir Dipivoxil,1,67,0.014705882352941176
 Cyproheptadine,1,68,0.014492753623188406
 Procarbazine,2,137,0.014492753623188406
-Clobetasol propionate,1,68,0.014492753623188406
 Diethylpropion,1,68,0.014492753623188406
+Clobetasol propionate,1,68,0.014492753623188406
 Verapamil,2,138,0.014388489208633094
 Roflumilast,1,69,0.014285714285714285
-Dextrothyroxine,1,71,0.013888888888888888
-Abiraterone,1,71,0.013888888888888888
 Levothyroxine,1,71,0.013888888888888888
-Simvastatin,2,143,0.013888888888888888
+Abiraterone,1,71,0.013888888888888888
 Fluocinolone Acetonide,2,143,0.013888888888888888
-Fludarabine,2,145,0.0136986301369863
+Simvastatin,2,143,0.013888888888888888
+Dextrothyroxine,1,71,0.013888888888888888
 Floxuridine,1,72,0.0136986301369863
+Fludarabine,2,145,0.0136986301369863
 Lapatinib,1,73,0.013513513513513514
 Amprenavir,1,73,0.013513513513513514
 Desloratadine,1,73,0.013513513513513514
 Estrone,1,74,0.013333333333333334
-Rosiglitazone,1,76,0.012987012987012988
-Bepridil,1,76,0.012987012987012988
-Zafirlukast,1,76,0.012987012987012988
 Ethinyl Estradiol,2,153,0.012987012987012988
+Rosiglitazone,1,76,0.012987012987012988
+Zafirlukast,1,76,0.012987012987012988
+Bepridil,1,76,0.012987012987012988
 Cimetidine,1,77,0.01282051282051282
 Sulfadiazine,1,78,0.012658227848101266
 Leflunomide,3,240,0.012448132780082987
@@ -201,21 +201,21 @@ Candesartan,1,83,0.011904761904761904
 Phenobarbital,1,84,0.011764705882352941
 Orlistat,2,170,0.011695906432748537
 Cyclosporine,4,344,0.011594202898550725
-Theophylline,1,86,0.011494252873563218
 Methyldopa,1,86,0.011494252873563218
+Theophylline,1,86,0.011494252873563218
 Niacin,2,177,0.011235955056179775
 Rufinamide,1,88,0.011235955056179775
 Nilutamide,1,89,0.011111111111111112
-Fingolimod,1,90,0.01098901098901099
-Fulvestrant,1,90,0.01098901098901099
 Amiloride,1,90,0.01098901098901099
-Flutamide,1,90,0.01098901098901099
+Fulvestrant,1,90,0.01098901098901099
+Fingolimod,1,90,0.01098901098901099
 Hydralazine,1,90,0.01098901098901099
+Flutamide,1,90,0.01098901098901099
 Pravastatin,2,184,0.010810810810810811
-Didanosine,1,92,0.010752688172043012
 Pamidronate,2,185,0.010752688172043012
-Clonidine,2,186,0.0106951871657754
+Didanosine,1,92,0.010752688172043012
 Cladribine,2,186,0.0106951871657754
+Clonidine,2,186,0.0106951871657754
 Toremifene,1,93,0.010638297872340425
 Pindolol,1,93,0.010638297872340425
 Formoterol,2,188,0.010582010582010581
@@ -227,18 +227,18 @@ Crizotinib,1,99,0.01
 Enalapril,2,200,0.009950248756218905
 Benazepril,1,101,0.00980392156862745
 Nadolol,1,102,0.009708737864077669
-Ifosfamide,3,311,0.009615384615384616
-Telbivudine,1,103,0.009615384615384616
 Lacosamide,1,103,0.009615384615384616
+Ifosfamide,3,311,0.009615384615384616
 Telmisartan,2,207,0.009615384615384616
+Telbivudine,1,103,0.009615384615384616
 Estradiol valerate/Dienogest,1,104,0.009523809523809525
-Isradipine,1,106,0.009345794392523364
 Glipizide,1,106,0.009345794392523364
+Isradipine,1,106,0.009345794392523364
 Guanfacine,1,107,0.009259259259259259
 Lamivudine,2,216,0.009216589861751152
-Salbutamol,2,217,0.009174311926605505
 Olopatadine,1,108,0.009174311926605505
 Nicardipine,1,108,0.009174311926605505
+Salbutamol,2,217,0.009174311926605505
 Paclitaxel,4,442,0.009029345372460496
 Tamoxifen,2,222,0.008968609865470852
 Felodipine,1,111,0.008928571428571428
@@ -248,8 +248,8 @@ Apraclonidine,1,112,0.008849557522123894
 Zoledronate,2,232,0.008583690987124463
 Gemfibrozil,1,116,0.008547008547008548
 Budesonide,2,235,0.00847457627118644
-Pioglitazone,1,118,0.008403361344537815
 Degarelix,1,118,0.008403361344537815
+Pioglitazone,1,118,0.008403361344537815
 Esmolol,1,118,0.008403361344537815
 Perindopril,2,239,0.008333333333333333
 Nevirapine,1,120,0.008264462809917356
@@ -261,15 +261,15 @@ Penicillamine,1,122,0.008130081300813009
 Hydrochlorothiazide,2,246,0.008097165991902834
 Ticagrelor,1,123,0.008064516129032258
 Pimecrolimus,1,124,0.008
-Goserelin,2,249,0.008
 Pemetrexed,1,124,0.008
-Glimepiride,1,126,0.007874015748031496
+Goserelin,2,249,0.008
 Gefitinib,1,126,0.007874015748031496
-Conjugated Estrogens,2,255,0.0078125
+Glimepiride,1,126,0.007874015748031496
 Sitagliptin,1,127,0.0078125
+Conjugated Estrogens,2,255,0.0078125
 Exemestane,1,128,0.007751937984496124
-Nelfinavir,1,130,0.007633587786259542
 Acebutolol,1,130,0.007633587786259542
+Nelfinavir,1,130,0.007633587786259542
 Stavudine,1,131,0.007575757575757576
 Betaxolol,2,263,0.007575757575757576
 Labetalol,1,133,0.007462686567164179
@@ -285,30 +285,30 @@ Nisoldipine,1,155,0.00641025641025641
 Amlodipine,1,155,0.00641025641025641
 Mycophenolate mofetil,3,488,0.006134969325153374
 Valproic Acid,2,326,0.0061162079510703364
+Clindamycin,1,163,0.006097560975609756
 Sunitinib,2,327,0.006097560975609756
 Bromocriptine,1,163,0.006097560975609756
-Clindamycin,1,163,0.006097560975609756
 Brimonidine,1,164,0.006060606060606061
 Fluticasone Propionate,1,166,0.005988023952095809
 Salmeterol,1,167,0.005952380952380952
-Quinidine,1,171,0.005813953488372093
 Quinine,1,171,0.005813953488372093
+Quinidine,1,171,0.005813953488372093
 Anastrozole,1,172,0.005780346820809248
 Letrozole,1,172,0.005780346820809248
 Daunorubicin,1,177,0.0056179775280898875
 Clofarabine,1,177,0.0056179775280898875
 Topiramate,3,535,0.005597014925373134
 Propofol,1,178,0.00558659217877095
-Pentostatin,1,179,0.005555555555555556
 Anagrelide,1,179,0.005555555555555556
-Estropipate,1,181,0.005494505494505495
-Metoprolol,1,181,0.005494505494505495
+Pentostatin,1,179,0.005555555555555556
 Guanabenz,1,181,0.005494505494505495
+Metoprolol,1,181,0.005494505494505495
+Estropipate,1,181,0.005494505494505495
 Galantamine,1,184,0.005405405405405406
 Dorzolamide,1,184,0.005405405405405406
 Nicotine,1,185,0.005376344086021506
-Travoprost,1,186,0.0053475935828877
 Zidovudine,1,186,0.0053475935828877
+Travoprost,1,186,0.0053475935828877
 Midazolam,1,188,0.005291005291005291
 Brinzolamide,1,192,0.0051813471502590676
 Levetiracetam,1,194,0.005128205128205128
@@ -323,15 +323,15 @@ Hyoscyamine,1,208,0.004784688995215311
 Pilocarpine,1,212,0.004694835680751174
 Fosphenytoin,1,212,0.004694835680751174
 Quinidine barbiturate,1,221,0.0045045045045045045
-Vandetanib,1,222,0.004484304932735426
 Estradiol,2,445,0.004484304932735426
+Vandetanib,1,222,0.004484304932735426
 Indinavir,1,223,0.004464285714285714
-Vigabatrin,1,226,0.004405286343612335
 Alitretinoin,2,453,0.004405286343612335
+Vigabatrin,1,226,0.004405286343612335
 Fenofibrate,1,228,0.004366812227074236
 Acamprosate,1,229,0.004347826086956522
-Chenodeoxycholic acid,1,230,0.004329004329004329
 Ursodeoxycholic acid,1,230,0.004329004329004329
+Chenodeoxycholic acid,1,230,0.004329004329004329
 Pazopanib,1,231,0.004310344827586207
 Diazepam,1,235,0.00423728813559322
 Clomifene,1,236,0.004219409282700422
@@ -340,8 +340,8 @@ Indapamide,1,243,0.004098360655737705
 Diltiazem,1,243,0.004098360655737705
 Carvedilol,1,249,0.004
 Busulfan,1,254,0.00392156862745098
-Allopurinol,1,255,0.00390625
 Felbamate,1,255,0.00390625
+Allopurinol,1,255,0.00390625
 Cetirizine,1,255,0.00390625
 Doxazosin,1,256,0.0038910505836575876
 Efavirenz,1,257,0.003875968992248062
@@ -356,12 +356,12 @@ Acitretin,1,284,0.0035087719298245615
 Delavirdine,1,287,0.003472222222222222
 Bexarotene,1,288,0.0034602076124567475
 Dasatinib,1,288,0.0034602076124567475
-Clonazepam,1,295,0.0033783783783783786
 Octreotide,1,295,0.0033783783783783786
+Clonazepam,1,295,0.0033783783783783786
 Varenicline,1,297,0.003355704697986577
 Phenytoin,1,300,0.0033222591362126247
-Esomeprazole,1,302,0.0033003300330033004
 Omeprazole,1,302,0.0033003300330033004
+Esomeprazole,1,302,0.0033003300330033004
 Oxcarbazepine,1,304,0.003278688524590164
 Progesterone,1,315,0.0031645569620253164
 Carbamazepine,1,337,0.0029585798816568047
@@ -377,8 +377,8 @@ Medroxyprogesterone Acetate,1,403,0.0024752475247524753
 Riluzole,1,408,0.0024449877750611247
 Everolimus,1,417,0.0023923444976076554
 Memantine,1,443,0.0022522522522522522
-Isotretinoin,1,453,0.0022026431718061676
 Tretinoin,1,453,0.0022026431718061676
+Isotretinoin,1,453,0.0022026431718061676
 Rivastigmine,1,468,0.0021321961620469083
 Lenalidomide,1,502,0.0019880715705765406
 Bupropion,1,520,0.0019193857965451055
--- a/neo4j_csv/analysis_symptom_triangle.csv
+++ b/neo4j_csv/analysis_symptom_triangle.csv
@@ -1,95 +1,95 @@
 symptom,num_diseases,num_treating_drugs,drugs_with_side_effects,impact_score
-Vomiting,38,123,114,4674
-Fatigue,25,137,131,3425
-Psychophysiologic Disorders,18,170,160,3060
-Birth Weight,14,168,159,2352
-Paresthesia,26,87,83,2262
+Edema,49,216,204,10584
+Body Weight,23,169,159,3887
+Fever of Unknown Origin,25,107,98,2675
+Neurologic Manifestations,28,84,79,2352
 "Hearing Loss, Sensorineural",24,70,65,1680
-Dyspnea,21,77,75,1617
-Cerebellar Ataxia,17,84,82,1428
-Cough,16,86,83,1376
-"Purpura, Thrombocytopenic, Idiopathic",15,89,83,1335
-Muscular Atrophy,16,81,77,1296
-Sleep Apnea Syndromes,12,95,90,1140
-Ataxia,16,68,67,1088
-Intellectual Disability,17,59,58,1003
-"Purpura, Thrombocytopenic",14,70,64,980
-Flushing,12,75,73,900
-Asthenia,13,68,66,884
-"Obesity, Abdominal",8,108,103,864
-Sciatica,15,50,48,750
-Aphasia,13,57,57,741
-Respiratory Sounds,11,67,66,737
-Ataxia Telangiectasia,13,49,47,637
-Vertigo,13,48,46,624
-"Urinary Bladder, Neurogenic",16,37,36,592
-"Purpura, Thrombotic Thrombocytopenic",7,84,81,588
-Syncope,11,48,47,528
+Constipation,21,75,70,1575
+Polyuria,12,101,96,1212
+Facial Pain,17,66,63,1122
+Sensation Disorders,16,68,64,1088
+Facial Paralysis,19,56,53,1064
+Quadriplegia,17,61,59,1037
+Oral Manifestations,15,62,57,930
+Pelvic Pain,17,49,47,833
+Hearing Disorders,18,46,45,828
+Hemoptysis,16,50,49,800
+Angina Pectoris,8,85,80,680
+Scotoma,12,55,54,660
+Weight Loss,9,62,60,558
+Horner Syndrome,13,42,41,546
+Hearing Loss,15,36,35,540
+Torticollis,14,37,35,518
 Hyperventilation,7,74,73,518
+Cyanosis,8,64,63,512
 Amnesia,10,50,50,500
 Hyperalgesia,10,48,46,480
-Voice Disorders,9,52,51,468
 Emaciation,8,57,54,456
-Flatulence,8,53,48,424
-Cerebrospinal Fluid Rhinorrhea,10,39,38,390
-Eye Hemorrhage,8,47,44,376
-"Hearing Loss, High-Frequency",10,37,36,370
+Dysphonia,8,55,53,440
+"Jaundice, Obstructive",14,30,29,420
+Mobility Limitation,9,44,42,396
+Pupil Disorders,10,37,37,370
 Chronic Pain,8,46,44,368
-Olfaction Disorders,10,36,36,360
-"Urinary Bladder, Overactive",6,59,58,354
-Color Vision Defects,9,39,39,351
-Acute Coronary Syndrome,6,47,46,282
-Pruritus Ani,6,43,39,258
-Eye Pain,7,36,35,252
+"Purpura, Schoenlein-Henoch",10,36,32,360
+Dystonia,9,37,37,333
+"Gait Disorders, Neurologic",11,26,25,286
+Tonic Pupil,5,57,56,285
+Vitreous Hemorrhage,8,34,33,272
+Agraphia,8,32,32,256
 Agnosia,7,36,36,252
-"Hearing Loss, Bilateral",8,30,29,240
-"Hearing Loss, Noise-Induced",3,80,74,240
-"Diarrhea, Infantile",7,34,28,238
+Eye Pain,7,36,35,252
+Perceptual Disorders,11,22,22,242
 Tremor,5,46,45,230
-Choroid Hemorrhage,6,34,33,204
-Sarcopenia,5,39,38,195
-"Hearing Loss, Central",6,32,31,192
-Hiccup,7,27,27,189
+"Aging, Premature",6,38,36,228
+"Sleep Apnea, Central",5,45,45,225
+Tinea Pedis,5,43,41,215
+Pain Threshold,7,29,28,203
+"Dyslexia, Acquired",7,27,27,189
+"Aphasia, Wernicke",5,36,36,180
 Phantom Limb,6,30,28,180
-Thinness,5,36,35,180
+Hyphema,5,34,33,170
+Cerebrospinal Fluid Leak,7,24,23,168
+Prosopagnosia,5,33,33,165
+Postoperative Nausea and Vomiting,4,39,38,156
+Bulimia,9,17,17,153
 Stuttering,6,25,25,150
-Gait Ataxia,6,22,22,132
+Kearns-Sayre Syndrome,5,30,30,150
+Hydrops Fetalis,6,22,22,132
 Huntington Disease,8,16,16,128
-"Syncope, Vasovagal",4,32,32,128
-Miosis,4,27,27,108
-Athetosis,3,36,36,108
-"Purpura, Hyperglobulinemic",4,24,20,96
-Metatarsalgia,3,27,25,81
-Toothache,5,16,16,80
-Ageusia,3,26,24,78
-Rett Syndrome,3,25,25,75
+Catalepsy,5,25,25,125
+Chills,3,39,35,117
+Pseudobulbar Palsy,3,37,37,111
+Photophobia,4,27,27,108
+Seizures,3,32,32,96
+Pruritus Vulvae,3,30,28,90
+Sneezing,2,43,42,86
+"Angina, Unstable",3,28,27,84
+Parasomnias,3,25,25,75
+De Lange Syndrome,4,18,14,72
 Post-Exercise Hypotension,1,68,63,68
-Fasciculation,4,15,15,60
-Dyssomnias,2,29,28,58
-Hyperemesis Gravidarum,3,18,18,54
+"Paraparesis, Spastic",4,16,16,64
+"Amnesia, Transient Global",2,29,29,58
 Respiratory Paralysis,4,13,13,52
-Nocturnal Paroxysmal Dystonia,2,25,25,50
-Hyperesthesia,3,14,13,42
+Muscle Spasticity,4,12,12,48
+Hyperoxia,3,16,16,48
+Hyperphagia,3,15,15,45
+Anomia,4,11,11,44
 Gerstmann Syndrome,3,13,13,39
-Polydipsia,4,9,9,36
-Urinoma,3,12,12,36
-Eructation,2,15,13,30
-Ophthalmoplegic Migraine,2,14,14,28
-Sleep Arousal Disorders,1,25,25,25
+Breakthrough Pain,2,18,18,36
+Neuroacanthocytosis,1,25,25,25
 Aphonia,3,8,8,24
-Reticulocytosis,2,11,9,22
+Presbycusis,4,6,6,24
 Adrenoleukodystrophy,2,11,11,22
-Muscle Hypertonia,2,11,11,22
-Halitosis,4,4,4,16
-"Apraxia, Ideomotor",3,5,5,15
+WAGR Syndrome,1,13,13,13
 Orthostatic Intolerance,1,11,11,11
-Prader-Willi Syndrome,1,11,11,11
-Susac Syndrome,1,11,11,11
 "Aphasia, Primary Progressive",2,4,4,8
-Benign Paroxysmal Positional Vertigo,1,7,7,7
-Anhedonia,4,1,1,4
-Striae Distensae,1,2,2,2
-Fetal Weight,2,1,1,2
-Wolfram Syndrome,1,1,1,1
-"Dyskinesia, Drug-Induced",5,0,0,0
-Nocturnal Myoclonus Syndrome,5,0,0,0
+Alice in Wonderland Syndrome,1,7,7,7
+Usher Syndromes,2,2,2,4
+Waterhouse-Friderichsen Syndrome,1,0,0,0
+"Polydipsia, Psychogenic",1,0,0,0
+Gait Apraxia,1,0,0,0
+Machado-Joseph Disease,2,0,0,0
+Alien Hand Syndrome,1,0,0,0
+Lipoid Proteinosis of Urbach and Wiethe,1,0,0,0
+"Akathisia, Drug-Induced",7,0,0,0
+Systolic Murmurs,1,0,0,0
--- a/neo4j_csv/edges_associates.csv
+++ b/neo4j_csv/edges_associates.csv
--- a/neo4j_csv/edges_binds.csv
+++ b/neo4j_csv/edges_binds.csv
--- a/neo4j_csv/edges_causes.csv
+++ b/neo4j_csv/edges_causes.csv
--- a/neo4j_csv/edges_covaries.csv
+++ b/neo4j_csv/edges_covaries.csv
--- a/neo4j_csv/edges_downregulates.csv
+++ b/neo4j_csv/edges_downregulates.csv
--- a/neo4j_csv/edges_expresses.csv
+++ b/neo4j_csv/edges_expresses.csv
--- a/neo4j_csv/edges_includes.csv
+++ b/neo4j_csv/edges_includes.csv
--- a/neo4j_csv/edges_interacts.csv
+++ b/neo4j_csv/edges_interacts.csv
--- a/neo4j_csv/edges_localizes.csv
+++ b/neo4j_csv/edges_localizes.csv
--- a/neo4j_csv/edges_palliates.csv
+++ b/neo4j_csv/edges_palliates.csv
@@ -0,0 +1,391 @@
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--- a/neo4j_csv/edges_participates.csv
+++ b/neo4j_csv/edges_participates.csv
--- a/neo4j_csv/edges_presents.csv
+++ b/neo4j_csv/edges_presents.csv
--- a/neo4j_csv/edges_regulates.csv
+++ b/neo4j_csv/edges_regulates.csv
--- a/neo4j_csv/edges_resembles.csv
+++ b/neo4j_csv/edges_resembles.csv
--- a/neo4j_csv/edges_treats.csv
+++ b/neo4j_csv/edges_treats.csv
@@ -0,0 +1,756 @@
+source,target
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--- a/neo4j_csv/edges_upregulates.csv
+++ b/neo4j_csv/edges_upregulates.csv