ETL_Datamanagement/neo4j_csv/nodes_Pharmacologic_Class.csv

1	id	name	source	license	url	description	chromosome	inchikey	inchi	mesh_id	bto_id	class_type
2	N0000007632	Thyroxine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007632							Chemical/Ingredient
3	N0000011272	Thiazolidinediones	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011272							Chemical/Ingredient
4	N0000178477	Decreased Blood Pressure	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000178477							Physiologic Effect
5	N0000010288	Osmotic Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000010288							Mechanism of Action
6	N0000190114	Cytochrome P450 3A Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190114							Mechanism of Action
7	N0000175799	Dopamine D2 Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175799							Mechanism of Action
8	N0000000114	Dopamine Uptake Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000114							Mechanism of Action
9	N0000175732	Neuromuscular Nondepolarizing Blockade	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175732							Physiologic Effect
10	N0000175729	Central Nervous System Stimulation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175729							Physiologic Effect
11	N0000008779	Decreased Parasympathetic Acetylcholine Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008779							Physiologic Effect
12	N0000007618	Ergolines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007618							Chemical/Ingredient
13	N0000175654	Gonadotropin Releasing Hormone Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175654							Mechanism of Action
14	N0000167094	Benzothiazoles	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000167094							Chemical/Ingredient
15	N0000020024	Sclerosing Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020024							Mechanism of Action
16	N0000175379	Arteriolar Vasodilation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175379							Physiologic Effect
17	N0000175764	Serotonin 1d Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175764							Mechanism of Action
18	N0000175914	Increased Coagulation Factor VIII Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175914							Physiologic Effect
19	N0000007151	Folic Acid	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007151							Chemical/Ingredient
20	N0000008053	Sulfones	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008053							Chemical/Ingredient
21	N0000191267	Cytochrome P450 2D6 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191267							Mechanism of Action
22	N0000175089	Calcium Chelating Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175089							Mechanism of Action
23	N0000008486	Decreased Central Nervous System Disorganized Electrical Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008486							Physiologic Effect
24	N0000008479	Decreased Cell Wall Synthesis & Repair	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008479							Physiologic Effect
25	N0000009947	Nucleoside Reverse Transcriptase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009947							Mechanism of Action
26	N0000009176	Increased Cellular Death	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009176							Physiologic Effect
27	N0000011281	Penicillins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011281							Chemical/Ingredient
28	N0000000070	Angiotensin 2 Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000070							Mechanism of Action
29	N0000175087	Urease Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175087							Mechanism of Action
30	N0000185007	Adrenergic beta3-Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185007							Mechanism of Action
31	N0000000083	Leukotriene Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000083							Mechanism of Action
32	N0000191264	P-Glycoprotein Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191264							Mechanism of Action
33	N0000011414	Ketolides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011414							Chemical/Ingredient
34	N0000007647	Nitrates	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007647							Chemical/Ingredient
35	N0000187062	Cytochrome P450 2C8 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000187062							Mechanism of Action
36	N0000006277	Vitamin D	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006277							Chemical/Ingredient
37	N0000191272	UGT1A1 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191272							Mechanism of Action
38	N0000175915	Increased Coagulation Factor VIII Concentration	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175915							Physiologic Effect
39	N0000175960	Increased Glutathione Concentration	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175960							Physiologic Effect
40	N0000008953	Decreased Striated Muscle Contraction	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008953							Physiologic Effect
41	N0000010262	Neurokinin 1 Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000010262							Mechanism of Action
42	N0000009282	Increased Dopamine Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009282							Physiologic Effect
43	N0000182138	Cytochrome P450 1A2 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182138							Mechanism of Action
44	N0000175359	Increased Diuresis	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175359							Physiologic Effect
45	N0000187063	Cytochrome P450 2C8 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000187063							Mechanism of Action
46	N0000175512	Methylated Sulfonamides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175512							Chemical/Ingredient
47	N0000190111	Organic Anion Transporter 3 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190111							Mechanism of Action
48	N0000006999	Urea	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006999							Chemical/Ingredient
49	N0000191265	Organic Cation Transporter 1 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191265							Mechanism of Action
50	N0000000160	Cyclooxygenase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000160							Mechanism of Action
51	N0000000151	Histamine H2 Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000151							Mechanism of Action
52	N0000007544	Phenothiazines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007544							Chemical/Ingredient
53	N0000009948	Non-Nucleoside Reverse Transcriptase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009948							Mechanism of Action
54	N0000007715	Catecholamines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007715							Chemical/Ingredient
55	N0000005760	Aminosalicylic Acids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000005760							Chemical/Ingredient
56	N0000175516	RNA Synthetase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175516							Mechanism of Action
57	N0000171207	Porphyrinogens	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000171207							Chemical/Ingredient
58	N0000008859	Decreased Renal K+ Excretion	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008859							Physiologic Effect
59	N0000009371	Increased Large Intestinal Motility	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009371							Physiologic Effect
60	N0000009963	Thrombin Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009963							Mechanism of Action
61	N0000000116	GABA B Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000116							Mechanism of Action
62	N0000008832	Decreased Platelet Aggregation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008832							Physiologic Effect
63	N0000007659	Nitrogen Mustard Compounds	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007659							Chemical/Ingredient
64	N0000000115	Progestational Hormone Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000115							Mechanism of Action
65	N0000008836	Decreased Prostaglandin Production	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008836							Physiologic Effect
66	N0000184306	Cell-mediated Immunity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000184306							Physiologic Effect
67	N0000010259	Ultrasound Contrast Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000010259							Mechanism of Action
68	N0000008683	Decreased Leukotriene Production	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008683							Physiologic Effect
69	N0000175830	Inhibit Ovum Fertilization	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175830							Physiologic Effect
70	N0000175080	Aromatase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175080							Mechanism of Action
71	N0000187064	Cytochrome P450 2B6 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000187064							Mechanism of Action
72	N0000175967	Thrombopoietin Receptor Interactions	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175967							Mechanism of Action
73	N0000000235	Carbonic Anhydrase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000235							Mechanism of Action
74	N0000006269	Vitamin A	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006269							Chemical/Ingredient
75	N0000007909	Psoralens	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007909							Chemical/Ingredient
76	N0000175921	Adrenal Steroid Synthesis Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175921							Mechanism of Action
77	N0000007529	Macrolides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007529							Chemical/Ingredient
78	N0000006996	Cholecalciferol	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006996							Chemical/Ingredient
79	N0000009911	Venous Vasodilation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009911							Physiologic Effect
80	N0000185499	Guanylate Cyclase Activators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185499							Mechanism of Action
81	N0000000146	Androgen Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000146							Mechanism of Action
82	N0000006496	Nicotine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006496							Chemical/Ingredient
83	N0000175808	Hydroxyphenylpyruvate Dioxygenase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175808							Mechanism of Action
84	N0000175728	Central Nervous System Depression	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175728							Physiologic Effect
85	N0000007641	Nicotinic Acids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007641							Chemical/Ingredient
86	N0000007568	Oxazolidinones	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007568							Chemical/Ingredient
87	N0000175850	Melanin Synthesis Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175850							Mechanism of Action
88	N0000190482	Phenylalanine Hydroxylase Activators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190482							Mechanism of Action
89	N0000170119	PPAR gamma	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000170119							Chemical/Ingredient
90	N0000009456	Increased Norepinephrine Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009456							Physiologic Effect
91	N0000000206	Xanthine Oxidase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000206							Mechanism of Action
92	N0000009871	Stimulation Large Intestine Fluid/Electrolyte Secretion	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009871							Physiologic Effect
93	N0000009724	Inhibition Gastric Acid Secretion	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009724							Physiologic Effect
94	N0000000183	Acetyl Aldehyde Dehydrogenase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000183							Mechanism of Action
95	N0000009269	Increased Cytokine Production	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009269							Physiologic Effect
96	N0000175073	Platinum-containing Compounds	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175073							Chemical/Ingredient
97	N0000000207	Histamine Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000207							Mechanism of Action
98	N0000175817	Serotonin 3 Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175817							Mechanism of Action
99	N0000175635	Factor Xa Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175635							Mechanism of Action
100	N0000007822	Polymyxins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007822							Chemical/Ingredient
101	N0000007542	Benzodiazepines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007542							Chemical/Ingredient
102	N0000006801	Bile Acids and Salts	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006801							Chemical/Ingredient
103	N0000009801	Photosensitizing Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009801							Physiologic Effect
104	N0000000102	Norepinephrine Uptake Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000102							Mechanism of Action
105	N0000191280	Lipoglycopeptides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191280							Chemical/Ingredient
106	N0000009526	Increased Prostaglandin Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009526							Physiologic Effect
107	N0000011310	Aldosterone Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011310							Mechanism of Action
108	N0000000154	Opioid Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000154							Mechanism of Action
109	N0000007196	Iodine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007196							Chemical/Ingredient
110	N0000182137	Cytochrome P450 2D6 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182137							Mechanism of Action
111	N0000007522	Allylamine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007522							Chemical/Ingredient
112	N0000020081	Increased Calcium-sensing Receptor Sensitivity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020081							Mechanism of Action
113	N0000175755	DOPA Decarboxylase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175755							Mechanism of Action
114	N0000191274	UGT2B15 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191274							Mechanism of Action
115	N0000007780	Vinca Alkaloids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007780							Chemical/Ingredient
116	N0000175450	Corticosteroid Hormone Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175450							Mechanism of Action
117	N0000000150	Protein Synthesis Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000150							Mechanism of Action
118	N0000175686	Competitive Opioid Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175686							Mechanism of Action
119	N0000000174	Opioid Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000174							Mechanism of Action
120	N0000006688	Carnitine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006688							Chemical/Ingredient
121	N0000175375	Peroxisome Proliferator-activated Receptor alpha Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175375							Mechanism of Action
122	N0000010217	Photoabsorption	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000010217							Mechanism of Action
123	N0000175788	Adenosine Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175788							Mechanism of Action
124	N0000175644	Decreased Autonomic Ganglionic Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175644							Physiologic Effect
125	N0000184148	Smoothened Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000184148							Mechanism of Action
126	N0000175763	Serotonin 1b Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175763							Mechanism of Action
127	N0000009905	Vascular Sclerosing Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009905							Physiologic Effect
128	N0000175075	Proteasome Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175075							Mechanism of Action
129	N0000007698	Biguanides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007698							Chemical/Ingredient
130	N0000009393	Increased Medullary Respiratory Drive	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009393							Physiologic Effect
131	N0000008016	Barbiturates	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008016							Chemical/Ingredient
132	N0000190109	Organic Anion Transporting Polypeptide 2B1 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190109							Mechanism of Action
133	N0000000104	Cholinergic Muscarinic Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000104							Mechanism of Action
134	N0000008065	Purines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008065							Chemical/Ingredient
135	N0000180999	Angiotensin 2 Type 1 Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000180999							Mechanism of Action
136	N0000175086	Phosphodiesterase 3 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175086							Mechanism of Action
137	N0000175970	Increased Platelet Production	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175970							Physiologic Effect
138	N0000191278	UGT1A9 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191278							Mechanism of Action
139	N0000009917	Adrenergic alpha1-Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009917							Mechanism of Action
140	N0000020026	Phosphodiesterase 5 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020026							Mechanism of Action
141	N0000175632	Decreased Fibrinolysis	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175632							Physiologic Effect
142	N0000184145	Chloride Channel Activation Potentiators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000184145							Mechanism of Action
143	N0000190118	Cytochrome P450 3A Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190118							Mechanism of Action
144	N0000020074	Phosphate Chelating Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020074							Mechanism of Action
145	N0000008217	Azoles	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008217							Chemical/Ingredient
146	N0000175547	Reduction Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175547							Mechanism of Action
147	N0000175917	Thyroid Hormone Synthesis Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175917							Mechanism of Action
148	N0000167510	Estrogens, Conjugated (USP)	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000167510							Chemical/Ingredient
149	N0000166743	Esters	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000166743							Chemical/Ingredient
150	N0000182960	Phosphodiesterase 4 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182960							Mechanism of Action
151	N0000175969	Increased Megakaryocyte Maturation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175969							Physiologic Effect
152	N0000175076	Protein Kinase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175076							Mechanism of Action
153	N0000186778	Microsomal Triglyceride Transfer Protein Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000186778							Mechanism of Action
154	N0000000166	alpha Glucosidase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000166							Mechanism of Action
155	N0000007961	Heparin, Low-Molecular-Weight	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007961							Chemical/Ingredient
156	N0000175513	Dipeptidase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175513							Mechanism of Action
157	N0000000191	Dihydrofolate Reductase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000191							Mechanism of Action
158	N0000185504	Cytochrome P450 2C9 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185504							Mechanism of Action
159	N0000007570	Pyridines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007570							Chemical/Ingredient
160	N0000175862	Magnetic Resonance Contrast Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175862							Mechanism of Action
161	N0000191258	RNA Replicase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191258							Mechanism of Action
162	N0000175459	Nucleoside Analog	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175459							Chemical/Ingredient
163	N0000178324	Increased Hematopoietic Stem Cell Mobilization	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000178324							Physiologic Effect
164	N0000011418	Streptogramins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011418							Chemical/Ingredient
165	N0000182140	Cytochrome P450 2C19 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182140							Mechanism of Action
166	N0000175370	Cholinergic Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175370							Mechanism of Action
167	N0000008553	Decreased Cholesterol Absorption	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008553							Physiologic Effect
168	N0000007620	Ergot Alkaloids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007620							Chemical/Ingredient
169	N0000007948	Tetracyclines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007948							Chemical/Ingredient
170	N0000000190	Histamine H1 Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000190							Mechanism of Action
171	N0000008330	Cardiac Rhythm Alteration	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008330							Physiologic Effect
172	N0000008054	Sulfonylurea Compounds	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008054							Chemical/Ingredient
173	N0000007770	Deoxyuridine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007770							Chemical/Ingredient
174	N0000000122	Adrenergic Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000122							Mechanism of Action
175	N0000000202	beta Lactamase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000202							Mechanism of Action
176	N0000007707	Diphosphonates	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007707							Chemical/Ingredient
177	N0000191423	Multidrug and Toxin Extrusion Transporter 1 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191423							Mechanism of Action
178	N0000175965	Increased Prothrombin Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175965							Physiologic Effect
179	N0000009022	Digestive/GI System Activity Alteration	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009022							Physiologic Effect
180	N0000007530	Anthracyclines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007530							Chemical/Ingredient
181	N0000006165	Triiodothyronine	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006165							Chemical/Ingredient
182	N0000008853	Decreased RNA Replication	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008853							Physiologic Effect
183	N0000175975	General Anesthesia	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175975							Physiologic Effect
184	N0000006014	Pyrethrins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006014							Chemical/Ingredient
185	N0000000069	Calcium Channel Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000069							Mechanism of Action
186	N0000008732	Decreased Mitosis	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008732							Physiologic Effect
187	N0000000168	Selective Estrogen Receptor Modulators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000168							Mechanism of Action
188	N0000009267	Increased Cytokine Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009267							Physiologic Effect
189	N0000006320	Vasopressins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006320							Chemical/Ingredient
190	N0000011311	Monobactams	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011311							Chemical/Ingredient
191	N0000187061	Organic Cation Transporter 2 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000187061							Mechanism of Action
192	N0000000209	Adrenergic alpha-Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000209							Mechanism of Action
193	N0000007621	Ergotamines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007621							Chemical/Ingredient
194	N0000175508	Lipopeptides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175508							Chemical/Ingredient
195	N0000175702	Partial Cholinergic Nicotinic Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175702							Mechanism of Action
196	N0000007681	Amides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007681							Chemical/Ingredient
197	N0000182728	Potassium Channel Openers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182728							Mechanism of Action
198	N0000000236	Alkylating Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000236							Mechanism of Action
199	N0000182638	HCV NS3/4A Protease Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182638							Mechanism of Action
200	N0000007566	Benzylamines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007566							Chemical/Ingredient
201	N0000178478	Increased Blood Pressure	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000178478							Physiologic Effect
202	N0000009923	Adrenergic beta1-Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009923							Mechanism of Action
203	N0000170118	PPAR alpha	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000170118							Chemical/Ingredient
204	N0000007893	Glycosaminoglycans	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007893							Chemical/Ingredient
205	N0000175445	Chemokine Co-receptor 5 Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175445							Mechanism of Action
206	N0000175721	Nonsteroidal Anti-inflammatory Compounds	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175721							Chemical/Ingredient
207	N0000009945	Antidiuretic Hormone Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009945							Mechanism of Action
208	N0000007606	Quinolones	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007606							Chemical/Ingredient
209	N0000011402	Estradiol Congeners	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011402							Chemical/Ingredient
210	N0000166469	Thiazides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000166469							Chemical/Ingredient
211	N0000009048	GI Motility Alteration	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009048							Physiologic Effect
212	N0000006290	Vitamin K	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006290							Chemical/Ingredient
213	N0000008157	Cardiac Glycosides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008157							Chemical/Ingredient
214	N0000191275	UGT1A3 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191275							Mechanism of Action
215	N0000175550	Decreased Immunologic Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175550							Physiologic Effect
216	N0000007663	Nitroimidazoles	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007663							Chemical/Ingredient
217	N0000011161	Cephalosporins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011161							Chemical/Ingredient
218	N0000175685	Partial Opioid Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175685							Mechanism of Action
219	N0000175372	Appetite Suppression	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175372							Physiologic Effect
220	N0000007889	Glycopeptides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007889							Chemical/Ingredient
221	N0000009982	Decreased Sebaceous Gland Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009982							Physiologic Effect
222	N0000008556	Decreased Coagulation Factor Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008556							Physiologic Effect
223	N0000175085	Microtubule Inhibition	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175085							Physiologic Effect
224	N0000000194	Somatostatin Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000194							Mechanism of Action
225	N0000190855	Vesicular Monoamine Transporter 2 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190855							Mechanism of Action
226	N0000009065	Hematologic Activity Alteration	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009065							Physiologic Effect
227	N0000184143	Carbamoyl Phosphate Synthetase 1 Activators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000184143							Mechanism of Action
228	N0000175733	Neuromuscular Depolarizing Blockade	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175733							Physiologic Effect
229	N0000175436	Neuraminidase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175436							Mechanism of Action
230	N0000191266	Cytochrome P450 1A2 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191266							Mechanism of Action
231	N0000007246	Estradiol	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007246							Chemical/Ingredient
232	N0000007706	Prostaglandins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007706							Chemical/Ingredient
233	N0000000196	GABA A Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000196							Mechanism of Action
234	N0000175542	M2 Protein Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175542							Mechanism of Action
235	N0000175624	mTOR Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175624							Mechanism of Action
236	N0000175955	5-Lipoxygenase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175955							Mechanism of Action
237	N0000182141	Cytochrome P450 3A4 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182141							Mechanism of Action
238	N0000190115	Cytochrome P450 3A5 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190115							Mechanism of Action
239	N0000175361	Catecholamine Synthesis Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175361							Mechanism of Action
240	N0000175460	Non-Nucleoside Analog	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175460							Chemical/Ingredient
241	N0000010258	X-Ray Contrast Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000010258							Mechanism of Action
242	N0000007672	Polyenes	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007672							Chemical/Ingredient
243	N0000020000	Receptor Tyrosine Kinase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020000							Mechanism of Action
244	N0000175735	Decreased Striated Muscle Tone	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175735							Physiologic Effect
245	N0000007556	Dihydropyridines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007556							Chemical/Ingredient
246	N0000009034	Emesis Suppression	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009034							Physiologic Effect
247	N0000008663	Decreased Immunologically Active Molecule Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008663							Physiologic Effect
248	N0000175761	Monoamine Oxidase-B Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175761							Mechanism of Action
249	N0000190110	Organic Anion Transporter 1 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190110							Mechanism of Action
250	N0000175084	Gonadotropin Releasing Hormone Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175084							Mechanism of Action
251	N0000009916	Lipase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009916							Mechanism of Action
252	N0000007683	Organometallic Compounds	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007683							Chemical/Ingredient
253	N0000175976	Local Anesthesia	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175976							Physiologic Effect
254	N0000175456	Chloride Channel Activators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175456							Mechanism of Action
255	N0000000111	Folic Acid Metabolism Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000111							Mechanism of Action
256	N0000009079	Increased Acetylcholine Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009079							Physiologic Effect
257	N0000185503	P-Glycoprotein Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185503							Mechanism of Action
258	N0000175964	Vitamin K Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175964							Mechanism of Action
259	N0000175982	Reversed Anticoagulation Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175982							Physiologic Effect
260	N0000175629	Increased Histamine Release	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175629							Physiologic Effect
261	N0000166489	Quaternary Ammonium Compounds	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000166489							Chemical/Ingredient
262	N0000191277	UGT1A6 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191277							Mechanism of Action
263	N0000007700	Retinoids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007700							Chemical/Ingredient
264	N0000009010	Decreased Tracheobronchial Stretch Receptor Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009010							Physiologic Effect
265	N0000190107	Organic Anion Transporting Polypeptide 1B1 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190107							Mechanism of Action
266	N0000000109	Serotonin Uptake Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000109							Mechanism of Action
267	N0000020060	DNA Polymerase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020060							Mechanism of Action
268	N0000009918	Adrenergic alpha2-Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009918							Mechanism of Action
269	N0000008867	Decreased Respiratory Secretion Viscosity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008867							Physiologic Effect
270	N0000020019	Glucosylceramide Synthase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020019							Mechanism of Action
271	N0000008118	Xanthines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008118							Chemical/Ingredient
272	N0000182147	Sigma-1 Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182147							Mechanism of Action
273	N0000000144	Iron Chelating Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000144							Mechanism of Action
274	N0000008841	Decreased Protein Synthesis	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008841							Physiologic Effect
275	N0000006806	Amino Acids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006806							Chemical/Ingredient
276	N0000009059	Genitourinary Arterial Vasodilation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009059							Physiologic Effect
277	N0000175533	Dyes	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175533							Mechanism of Action
278	N0000175851	Depigmenting Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175851							Physiologic Effect
279	N0000185607	Cytochrome P450 2C19 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185607							Mechanism of Action
280	N0000175628	Decreased Histamine Release	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175628							Physiologic Effect
281	N0000175651	Increased Sympathetic Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175651							Physiologic Effect
282	N0000009922	Adrenergic beta2-Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009922							Mechanism of Action
283	N0000185507	Cytochrome P450 2C9 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185507							Mechanism of Action
284	N0000175650	Decreased Sympathetic Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175650							Physiologic Effect
285	N0000191269	UDP Glucuronosyltransferases Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191269							Mechanism of Action
286	N0000175472	Metal Chelating Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175472							Mechanism of Action
287	N0000007911	Rifamycins	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007911							Chemical/Ingredient
288	N0000000125	Cholinergic Muscarinic Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000125							Mechanism of Action
289	N0000181815	Sphingosine 1-Phosphate Receptor Modulators	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000181815							Mechanism of Action
290	N0000007710	Prostaglandins E, Synthetic	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007710							Chemical/Ingredient
291	N0000191276	UGT1A4 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191276							Mechanism of Action
292	N0000175833	Acidifying Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175833							Mechanism of Action
293	N0000009924	Adrenergic beta2-Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009924							Mechanism of Action
294	N0000000243	Androgen Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000243							Mechanism of Action
295	N0000007983	Hydroxy Acids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007983							Chemical/Ingredient
296	N0000007883	Amphetamines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007883							Chemical/Ingredient
297	N0000175968	Thrombopoietin Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175968							Mechanism of Action
298	N0000175479	Amphenicols	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175479							Chemical/Ingredient
299	N0000006276	Vitamin B 12	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006276							Chemical/Ingredient
300	N0000175684	Full Opioid Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175684							Mechanism of Action
301	N0000191273	UGT2B7 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191273							Mechanism of Action
302	N0000171131	Allergens	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000171131							Chemical/Ingredient
303	N0000182143	P2Y12 Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182143							Mechanism of Action
304	N0000186774	Diarylquinolines	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000186774							Chemical/Ingredient
305	N0000007853	Aminoglycosides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007853							Chemical/Ingredient
306	N0000008478	Decreased Cell Wall Integrity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008478							Physiologic Effect
307	N0000000233	Nucleic Acid Synthesis Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000233							Mechanism of Action
308	N0000000239	P-Glycoprotein Interactions	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000239							Mechanism of Action
309	N0000000106	Prostaglandin Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000106							Mechanism of Action
310	N0000011294	Carbapenems	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011294							Chemical/Ingredient
311	N0000175442	Lincosamides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175442							Chemical/Ingredient
312	N0000000246	HIV Protease Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000246							Mechanism of Action
313	N0000181819	Uncompetitive NMDA Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000181819							Mechanism of Action
314	N0000175433	pleuromutilin	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175433							Chemical/Ingredient
315	N0000175549	Cystine Disulfide Reduction	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175549							Mechanism of Action
316	N0000191624	Cytochrome P450 1A Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000191624							Mechanism of Action
317	N0000005934	Progesterone	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000005934							Chemical/Ingredient
318	N0000175912	Dipeptidyl Peptidase 4 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175912							Mechanism of Action
319	N0000185506	Cytochrome P450 3A4 Inducers	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000185506							Mechanism of Action
320	N0000175448	Potassium Channel Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175448							Mechanism of Action
321	N0000187058	Sodium-Glucose Transporter 2 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000187058							Mechanism of Action
322	N0000008241	Androstanes	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008241							Chemical/Ingredient
323	N0000000176	Topoisomerase Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000176							Mechanism of Action
324	N0000007888	Bismuth	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007888							Chemical/Ingredient
325	N0000175374	Peroxisome Proliferator-activated Receptor Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175374							Mechanism of Action
326	N0000190113	Breast Cancer Resistance Protein Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190113							Mechanism of Action
327	N0000006337	Ergocalciferols	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000006337							Chemical/Ingredient
328	N0000175469	Pyrophosphate Analog	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175469							Chemical/Ingredient
329	N0000000250	Melatonin Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000250							Mechanism of Action
330	N0000175365	Bile-acid Binding Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175365							Mechanism of Action
331	N0000175730	Centrally-mediated Muscle Relaxation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175730							Physiologic Effect
332	N0000175366	Increased Diuresis at Loop of Henle	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175366							Physiologic Effect
333	N0000008010	Cannabinoids	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008010							Chemical/Ingredient
334	N0000007658	Nitrofurans	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000007658							Chemical/Ingredient
335	N0000020015	NMDA Receptor Antagonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000020015							Mechanism of Action
336	N0000009909	Vasodilation	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000009909							Physiologic Effect
337	N0000182139	Cytochrome P450 2B6 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000182139							Mechanism of Action
338	N0000175962	Lead Chelating Activity	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175962							Mechanism of Action
339	N0000011301	Progesterone Congeners	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011301							Chemical/Ingredient
340	N0000008638	Decreased GnRH Secretion	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008638							Physiologic Effect
341	N0000008048	Sulfonamides	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008048							Chemical/Ingredient
342	N0000190108	Organic Anion Transporting Polypeptide 1B3 Inhibitors	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000190108							Mechanism of Action
343	N0000000100	Estrogen Receptor Agonists	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000000100							Mechanism of Action
344	N0000008577	Decreased DNA Replication	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000008577							Physiologic Effect
345	N0000175972	Decreased Platelet Production	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000175972							Physiologic Effect
346	N0000011280	Prostaglandins I	FDA via DrugCentral	CC BY 4.0	http://purl.bioontology.org/ontology/NDFRT/N0000011280							Chemical/Ingredient