finishes setup

neo4jqueries/analysis_queries/query1.cypher

@@ -0,0 +1,6 @@
+// Drug similarity based on shared targets
+MATCH (c1:Compound)-[:BINDS]->(g:Gene)<-[:BINDS]-(c2:Compound)
+WHERE c1 <> c2
+RETURN c1.name AS Drug1, c2.name AS Drug2, count(g) AS SharedGenes
+ORDER BY SharedGenes DESC
+LIMIT 20;

neo4jqueries/analysis_queries/query2.cypher

@@ -0,0 +1,4 @@
+// Get count of nodes
+MATCH (n)
+RETURN labels(n) AS NodeType, count(*) AS Count
+ORDER BY Count DESC;

neo4jqueries/analysis_queries/query3.cypher

@@ -0,0 +1,5 @@
+// Drugs treating diseases that present specific symptoms
+MATCH (s:Symptom)<-[:PRESENTS]-(d:Disease)<-[:TREATS]-(c:Compound)
+RETURN s.name AS Symptom, c.name AS Drug, count(d) AS DiseaseCount
+ORDER BY DiseaseCount DESC
+LIMIT 20;

neo4jqueries/analysis_queries/query4.cypher

@@ -0,0 +1,5 @@
+// Top 10 diseases with the most associated symptoms
+MATCH (d:Disease)-[:PRESENTS]->(s:Symptom)
+RETURN d.name AS Disease, count(s) AS SymptomCount
+ORDER BY SymptomCount DESC
+LIMIT 10;

neo4jqueries/analysis_queries/query5.cypher

@@ -0,0 +1,9 @@
+// Drugs sharing the same side effects showing potential conflicts
+MATCH (c1:Compound)-[:BINDS]->(:Gene),
+      (c1)-[:TREATS]->(:Disease),
+      (c1)-[:TREATS]->(:Disease)<-[:TREATS]-(c2:Compound),
+      (c1)-[:BINDS]->(g:Gene)
+WHERE c1 <> c2
+RETURN c1.name AS Drug1, c2.name AS Drug2, count(g) AS SharedTargets
+ORDER BY SharedTargets DESC
+LIMIT 20;

neo4jqueries/analysis_queries/query6.cypher

@@ -0,0 +1,5 @@
+// Top 10 Drugs treating multiple Diseases
+MATCH (c:Compound)-[:TREATS]->(d:Disease)
+RETURN c.name AS Drug, count(d) AS DiseaseCount
+ORDER BY DiseaseCount DESC
+LIMIT 10;

neo4jqueries/analysis_queries/query7.cypher

@@ -0,0 +1,7 @@
+// Drugs treating diseases connected to the same genes
+MATCH (g:Gene)<-[:ASSOCIATES]-(d1:Disease)<-[:TREATS]-(c:Compound),
+      (g)<-[:ASSOCIATES]-(d2:Disease)
+WHERE NOT (c)-[:TREATS]->(d2)
+RETURN c.name AS Drug, d2.name AS CandidateDisease, count(g) AS SharedGenes
+ORDER BY SharedGenes DESC, Drug
+LIMIT 20;

neo4jqueries/analysis_queries/query8.cypher

@@ -0,0 +1,4 @@
+// LOOK for 999 Treatments for diseases
+MATCH p=()-[:TREATS]->() 
+RETURN p 
+LIMIT 999;

neo4jqueries/loadingQueriesNeo4j/LoadNodes.cypher

@@ -0,0 +1,19 @@
+// Genes
+LOAD CSV WITH HEADERS FROM 'file:///nodes_Gene.csv' AS row
+CREATE (g:Gene) SET g = row;
+
+// Diseases
+LOAD CSV WITH HEADERS FROM 'file:///nodes_Disease.csv' AS row
+CREATE (d:Disease) SET d = row;
+
+// Compounds
+LOAD CSV WITH HEADERS FROM 'file:///nodes_Compound.csv' AS row
+CREATE (c:Compound) SET c = row;
+
+// Symptoms
+LOAD CSV WITH HEADERS FROM 'file:///nodes_Symptom.csv' AS row
+CREATE (s:Symptom) SET s = row;
+
+// Side Effects
+LOAD CSV WITH HEADERS FROM 'file:///nodes_Side_Effect.csv' AS row
+CREATE (se:Side_Effect) SET se = row;

neo4jqueries/loadingQueriesNeo4j/LoadRelationshipsEdges_Associates copy.cypher

@@ -0,0 +1,4 @@
+LOAD CSV WITH HEADERS FROM 'file:///edges_treats.csv' AS row
+MATCH (source {id: row.source})            
+MATCH (target {id: row.target})
+CREATE (source)-[:TREATS]->(target);

neo4jqueries/loadingQueriesNeo4j/LoadRelationshipsEdges_Binds.cypher

@@ -0,0 +1,4 @@
+LOAD CSV WITH HEADERS FROM 'file:///edges_binds.csv' AS row
+MATCH (source {id: row.source})            
+MATCH (target {id: row.target})
+CREATE (source)-[:BINDS]->(target);

neo4jqueries/loadingQueriesNeo4j/LoadRelationshipsEdges_Causes copy 2.cypher

@@ -0,0 +1,4 @@
+LOAD CSV WITH HEADERS FROM 'file:///edges_interacts.csv' AS row
+MATCH (source {id: row.source})            
+MATCH (target {id: row.target})
+CREATE (source)-[:INTERACTS]->(target);

neo4jqueries/loadingQueriesNeo4j/LoadRelationshipsEdges_Covaries.cypher

@@ -0,0 +1,4 @@
+LOAD CSV WITH HEADERS FROM 'file:///edges_covaries.csv' AS row
+MATCH (source {id: row.source})            
+MATCH (target {id: row.target})
+CREATE (source)-[:COVARIES]->(target);

neo4jqueries/loadingQueriesNeo4j/LoadRelationshipsEdges_Interacts.cypher

@@ -0,0 +1,4 @@
+LOAD CSV WITH HEADERS FROM 'file:///edges_causes.csv' AS row
+MATCH (source {id: row.source})            
+MATCH (target {id: row.target})
+CREATE (source)-[:CAUSES]->(target);

neo4jqueries/loadingQueriesNeo4j/LoadRelationshipsEdges_Upregulates.cypher

@@ -0,0 +1,4 @@
+LOAD CSV WITH HEADERS FROM 'file:///edges_causes.csv' AS row
+MATCH (source {id: row.source})            
+MATCH (target {id: row.target})
+CREATE (source)-[:CAUSES]->(target);